STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cotCBSpore-coat protein, manganese catalase; Experimentally verified as part of mature spore proteome PMID:19542279. (190 aa)    
Predicted Functional Partners:
cotF
Spore coat peptide assembly protein CotF; Experimentally verified as part of mature spore proteome PMID:19542279.
 
  
 0.981
cotJB2
Spore coat peptide assembly protein CotJB 2; Experimentally verified as part of mature spore proteome PMID:19542279.
 
  
 0.944
sodA
Spore coat protein-superoxide dismutase (Mn); Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
   
  
 0.726
bclA2
Putative exosporium glycoprotein.
   
  
 0.669
cotE
Spore coat protein: peroxiredoxin/chitinase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
   
  
 0.660
cotB
Spore coat protein; Experimentally verified through RNA-seq as part of Spo0A regulated transcriptome: down-regulated in Spo0A mutant PMID:24568651. Experimentally verified as part of mature spore proteome PMID:19542279.
   
  
 0.621
CAJ67428.1
Uncharacterised protein; Experimentally verified as part of mature spore proteome PMID:19542279.
  
    0.606
spoIVA
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat and is required for proper coat localization to the forespore.
  
  
 0.576
bclA3
Exosporium glycoprotein BclA3.
  
  
 0.540
bclA1
Putative exosporium glycoprotein; Experimentally verified as part of mature spore proteome PMID:19542279.
  
  
 0.534
Your Current Organism:
Clostridioides difficile
NCBI taxonomy Id: 272563
Other names: C. difficile 630, Clostridioides difficile 630, Clostridium difficile 630, Clostridium difficile 630 (epidemic type X), Clostridium difficile str. 630, Clostridium difficile strain 630, Peptoclostridium difficile 630
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