node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CAJ68304.1 | ccpA | CD630_14390 | CD630_10640 | Putative transporter, LrgA family. | Transcriptional regulator, LacI family; Experimentally verified through RNA-seq as part of Spo0A regulated transcriptome: up-regulated in Spo0A mutant. Experimentally verified through Mass Spectrometry as part of Spo0A regulated proteome: up-regulated in Spo0A mutant PMID:24568651 .Experimentally verified as part of mature spore proteome PMID:19542279. | 0.488 |
CAJ68304.1 | codY | CD630_14390 | CD630_12750 | Putative transporter, LrgA family. | Transcriptional regulator, GTP-sensing pleiotropic repressor codY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family. | 0.639 |
CAJ68304.1 | tcdB | CD630_14390 | CD630_06600 | Putative transporter, LrgA family. | Toxin B. | 0.611 |
CAJ68304.1 | tcdC | CD630_14390 | CD630_06640 | Putative transporter, LrgA family. | Negative regulator of toxin gene expression. | 0.639 |
CAJ68304.1 | tcdE | CD630_14390 | CD630_06610 | Putative transporter, LrgA family. | Holin-like pore-forming protein. | 0.612 |
CAJ68304.1 | tcdR | CD630_14390 | CD630_06590 | Putative transporter, LrgA family. | Alternative RNA polymerase sigma factors. | 0.635 |
ccpA | CAJ68304.1 | CD630_10640 | CD630_14390 | Transcriptional regulator, LacI family; Experimentally verified through RNA-seq as part of Spo0A regulated transcriptome: up-regulated in Spo0A mutant. Experimentally verified through Mass Spectrometry as part of Spo0A regulated proteome: up-regulated in Spo0A mutant PMID:24568651 .Experimentally verified as part of mature spore proteome PMID:19542279. | Putative transporter, LrgA family. | 0.488 |
ccpA | codY | CD630_10640 | CD630_12750 | Transcriptional regulator, LacI family; Experimentally verified through RNA-seq as part of Spo0A regulated transcriptome: up-regulated in Spo0A mutant. Experimentally verified through Mass Spectrometry as part of Spo0A regulated proteome: up-regulated in Spo0A mutant PMID:24568651 .Experimentally verified as part of mature spore proteome PMID:19542279. | Transcriptional regulator, GTP-sensing pleiotropic repressor codY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family. | 0.757 |
ccpA | rpoA | CD630_10640 | CD630_00980 | Transcriptional regulator, LacI family; Experimentally verified through RNA-seq as part of Spo0A regulated transcriptome: up-regulated in Spo0A mutant. Experimentally verified through Mass Spectrometry as part of Spo0A regulated proteome: up-regulated in Spo0A mutant PMID:24568651 .Experimentally verified as part of mature spore proteome PMID:19542279. | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.400 |
ccpA | rpoC | CD630_10640 | CD630_00670 | Transcriptional regulator, LacI family; Experimentally verified through RNA-seq as part of Spo0A regulated transcriptome: up-regulated in Spo0A mutant. Experimentally verified through Mass Spectrometry as part of Spo0A regulated proteome: up-regulated in Spo0A mutant PMID:24568651 .Experimentally verified as part of mature spore proteome PMID:19542279. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.430 |
ccpA | tcdB | CD630_10640 | CD630_06600 | Transcriptional regulator, LacI family; Experimentally verified through RNA-seq as part of Spo0A regulated transcriptome: up-regulated in Spo0A mutant. Experimentally verified through Mass Spectrometry as part of Spo0A regulated proteome: up-regulated in Spo0A mutant PMID:24568651 .Experimentally verified as part of mature spore proteome PMID:19542279. | Toxin B. | 0.610 |
ccpA | tcdC | CD630_10640 | CD630_06640 | Transcriptional regulator, LacI family; Experimentally verified through RNA-seq as part of Spo0A regulated transcriptome: up-regulated in Spo0A mutant. Experimentally verified through Mass Spectrometry as part of Spo0A regulated proteome: up-regulated in Spo0A mutant PMID:24568651 .Experimentally verified as part of mature spore proteome PMID:19542279. | Negative regulator of toxin gene expression. | 0.485 |
ccpA | tcdR | CD630_10640 | CD630_06590 | Transcriptional regulator, LacI family; Experimentally verified through RNA-seq as part of Spo0A regulated transcriptome: up-regulated in Spo0A mutant. Experimentally verified through Mass Spectrometry as part of Spo0A regulated proteome: up-regulated in Spo0A mutant PMID:24568651 .Experimentally verified as part of mature spore proteome PMID:19542279. | Alternative RNA polymerase sigma factors. | 0.643 |
cdtR | codY | CD630_26030 | CD630_12750 | Clostridium difficile binary toxin regulatory gene, LytTR family. | Transcriptional regulator, GTP-sensing pleiotropic repressor codY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family. | 0.422 |
cdtR | tcdB | CD630_26030 | CD630_06600 | Clostridium difficile binary toxin regulatory gene, LytTR family. | Toxin B. | 0.620 |
cdtR | tcdC | CD630_26030 | CD630_06640 | Clostridium difficile binary toxin regulatory gene, LytTR family. | Negative regulator of toxin gene expression. | 0.612 |
cdtR | tcdE | CD630_26030 | CD630_06610 | Clostridium difficile binary toxin regulatory gene, LytTR family. | Holin-like pore-forming protein. | 0.611 |
cdtR | tcdR | CD630_26030 | CD630_06590 | Clostridium difficile binary toxin regulatory gene, LytTR family. | Alternative RNA polymerase sigma factors. | 0.634 |
codY | CAJ68304.1 | CD630_12750 | CD630_14390 | Transcriptional regulator, GTP-sensing pleiotropic repressor codY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family. | Putative transporter, LrgA family. | 0.639 |
codY | ccpA | CD630_12750 | CD630_10640 | Transcriptional regulator, GTP-sensing pleiotropic repressor codY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family. | Transcriptional regulator, LacI family; Experimentally verified through RNA-seq as part of Spo0A regulated transcriptome: up-regulated in Spo0A mutant. Experimentally verified through Mass Spectrometry as part of Spo0A regulated proteome: up-regulated in Spo0A mutant PMID:24568651 .Experimentally verified as part of mature spore proteome PMID:19542279. | 0.757 |