Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
etfA2Electron transfer flavoprotein alpha-subunit. (340 aa)    
Predicted Functional Partners:
etfB2
Electron transfer flavoprotein beta-subunit,core.
 0.997
etfB1
Beta-subunit of electron transfer flavoprotein; Experimentally verified through RNA-seq as part of Spo0A regulated transcriptome: up-regulated in Spo0A mutant PMID:24568651. Experimentally verified as part of mature spore proteome PMID:19542279.
 0.989
etfB3
Electron transfer flavoproteins subunit beta; Function experimentally characterised PMID:23772070. Experimentally verified through RNA-seq as part of Spo0A regulated transcriptome: down-regulated in Spo0A mutant. Experimentally verified through Mass Spectrometry as part of Spo0A regulated proteome: down-regulated in Spo0A mutant PMID:24568651.
 0.988
etfB4
Electron transfer flavoprotein subunit alpha.
 0.987
AcrC
Putative acyl-CoA dehydrogenase.
 
 0.975
bcd2
Butyryl-CoA dehydrogenase; Function experimentally characterised PMID:23772070. Experimentally verified through RNA-seq as part of Spo0A regulated transcriptome: down-regulated in Spo0A mutant. Experimentally verified through Mass Spectrometry as part of Spo0A regulated proteome: down-regulated in Spo0A mutant PMID:24568651. Experimentally verified as part of mature spore proteome PMID:19542279.
 
 0.920
acdB
Acyl-CoA dehydrogenase, short-chain specific; Experimentally verified through RNA-seq as part of Spo0A regulated transcriptome: up-regulated in Spo0A mutant PMID:24568651. Experimentally verified as part of mature spore proteome PMID:19542279.
 
 0.907
acoB
Acetoin dehydrogenase E1 component (TPP-dependent beta subunit).
  
 
 0.775
acoC
Acetoin dehydrogenase E2 component (dihydrolipoamide acetyltransferase).
   
  
 0.753
CAJ68026.1
Putative FAD-linked oxidase.
  
 
 0.733
Your Current Organism:
Clostridioides difficile
NCBI taxonomy Id: 272563
Other names: C. difficile 630, Clostridioides difficile 630, Clostridium difficile 630, Clostridium difficile 630 (epidemic type X), Clostridium difficile str. 630, Clostridium difficile strain 630, Peptoclostridium difficile 630
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