STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cotBSpore coat protein; Experimentally verified through RNA-seq as part of Spo0A regulated transcriptome: down-regulated in Spo0A mutant PMID:24568651. Experimentally verified as part of mature spore proteome PMID:19542279. (304 aa)    
Predicted Functional Partners:
feoA2
Ferrous iron transport protein.
  
    0.693
bclA2
Putative exosporium glycoprotein.
   
  
 0.631
bclA3
Exosporium glycoprotein BclA3.
   
  
 0.631
cotD
Spore coat protein, manganese catalase; Experimentally verified as part of mature spore proteome PMID:19542279.
   
  
 0.623
cotE
Spore coat protein: peroxiredoxin/chitinase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
   
  
 0.622
cotCB
Spore-coat protein, manganese catalase; Experimentally verified as part of mature spore proteome PMID:19542279.
   
  
 0.621
CdeC
Exosporium cysteine rich protein; Experimentally verified through RNA-seq as part of Spo0A regulated transcriptome: down-regulated in Spo0A mutant PMID:24568651. Experimentally verified as part of mature spore proteome PMID:19542279.
   
  
 0.613
cotG
Spore coat protein-manganese catalase; Experimentally verified as part of mature spore proteome PMID:19542279.
   
  
 0.606
bclA1
Putative exosporium glycoprotein; Experimentally verified as part of mature spore proteome PMID:19542279.
   
  
 0.601
cotF
Spore coat peptide assembly protein CotF; Experimentally verified as part of mature spore proteome PMID:19542279.
  
  
 0.591
Your Current Organism:
Clostridioides difficile
NCBI taxonomy Id: 272563
Other names: C. difficile 630, Clostridioides difficile 630, Clostridium difficile 630, Clostridium difficile 630 (epidemic type X), Clostridium difficile str. 630, Clostridium difficile strain 630, Peptoclostridium difficile 630
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