STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAJ69365.1Putative DNA uptake transporter. (278 aa)    
Predicted Functional Partners:
CAJ69362.1
Putative membrane protein.
  
 0.954
ComEB1
Putative dCMP deaminase.
 
    0.576
YqeN
Putative DNA polymerase III, delta subunit.
 
  
 0.530
CAJ69364.1
Uncharacterised protein; Experimentally verified as part of mature spore proteome PMID:19542279.
       0.524
CAJ69363.1
Gnat family acetyltransferase.
       0.515
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
 
    0.427
comE
Competence protein ComEA.
 
  
 0.406
CAJ68301.1
Putative hydrolase; Experimentally verified as part of mature spore proteome PMID:19542279.
  
     0.402
Your Current Organism:
Clostridioides difficile
NCBI taxonomy Id: 272563
Other names: C. difficile 630, Clostridioides difficile 630, Clostridium difficile 630, Clostridium difficile 630 (epidemic type X), Clostridium difficile str. 630, Clostridium difficile strain 630, Peptoclostridium difficile 630
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.