STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AppFABC-type transport system, ATP-binding protein; putative oligopeptide transport system; Belongs to the ABC transporter superfamily. (323 aa)    
Predicted Functional Partners:
appC
ABC-type transport system, oligopeptide-family permease protein.
 
 0.999
appB
ABC-type transport system, oligopeptide-family permease protein.
 
 0.997
AppD
ABC-type transport system, ATP-binding protein; Experimentally verified through Mass Spectrometry as part of Spo0A regulated proteome: up-regulated in Spo0A mutant PMID:24568651; Belongs to the ABC transporter superfamily.
 
 
0.996
oppB
ABC-type transport system, oligopeptide-family permease.
 
 0.993
oppC
ABC-type transport system, oligopeptide-family permease.
  
 0.993
appA
ABC-type transport system, oligopeptide-family solute-binding protein; Experimentally verified through Mass Spectrometry as part of Spo0A regulated proteome: up-regulated in Spo0A mutant PMID:24568651. Experimentally verified as part of mature spore proteome PMID:19542279.
 
 0.992
oppA
ABC-type transport system, oligopeptide-family extracellular solute-binding protein; Experimentally verified through Mass Spectrometry as part of Spo0A regulated proteome: down-regulated in Spo0A mutant PMID:24568651.
 
 0.986
oppD
ABC-type transport system, ATP-binding component; Belongs to the ABC transporter superfamily.
 
  
0.853
cbiO
ABC-type transport system, cobalt-specific ATP-binding protein; Part of an ABC transporter complex. Responsible for energy coupling to the transport system.
 
 
0.828
cbiQ
ABC-type transport system, cobalt-specific permease; Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
 
 
 0.781
Your Current Organism:
Clostridioides difficile
NCBI taxonomy Id: 272563
Other names: C. difficile 630, Clostridioides difficile 630, Clostridium difficile 630, Clostridium difficile 630 (epidemic type X), Clostridium difficile str. 630, Clostridium difficile strain 630, Peptoclostridium difficile 630
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