STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
slpAPrecursor of the S-layer proteins; Experimentally verified as part of mature spore proteome PMID:19542279. (719 aa)    
Predicted Functional Partners:
secA2
Protein translocase subunit secA 2; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
     
 0.767
fliC
Flagellin C; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
   
  
 0.626
cwp12
Cell wall binding protein cwp12.
 
   
0.625
CAJ68394.1
ABC-type transport system, permease.
  
     0.615
tcdB
Toxin B.
  
  
 0.613
CAJ69658.1
Putative glycosyl transferase, group 1.
  
    0.594
CAJ69663.1
Putative glycerophosphotransferase.
  
    0.566
fliD
Flagellar hook-associated protein 2 FliD (or HAP2); Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
   
  
 0.545
cwp11
Cell wall binding protein cwp11; Experimentally verified through Mass Spectrometry as part of Spo0A regulated proteome: down-regulated in Spo0A mutant PMID:24568651.
 
   
0.532
CAJ69604.1
Putative sporulation protein.
  
     0.516
Your Current Organism:
Clostridioides difficile
NCBI taxonomy Id: 272563
Other names: C. difficile 630, Clostridioides difficile 630, Clostridium difficile 630, Clostridium difficile 630 (epidemic type X), Clostridium difficile str. 630, Clostridium difficile strain 630, Peptoclostridium difficile 630
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.