STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AdhBAlcohol dehydrogenase. (381 aa)    
Predicted Functional Partners:
aldH
Aldehyde dehydrogenase (aldehyde:NAD+ oxidoreductase); Belongs to the aldehyde dehydrogenase family.
 
 0.979
eutE
Ethanolamine acetaldehyde oxydoreductase.
 
 0.963
sucD
Succinate-semialdehyde dehydrogenase (NAD(P)+); Experimentally verified through RNA-seq as part of Spo0A regulated transcriptome: up-regulated in Spo0A mutant PMID:24568651.
 
 
 0.930
adhE
Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
 
0.929
adhE1
Aldehyde-alcohol dehydrogenase; Experimentally verified as part of mature spore proteome PMID:19542279; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
 
0.928
hpdA
Putative 4-hydroxyphenylacetate decarboxylase,activating subunit HpdA; Activation of 4-hydroxyphenylacetate decarboxylase under anaerobic conditions by generation of an organic free radical.
  
  
 0.556
rex
Transcriptional regulator, Redox-sensing repressor Rex; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
  
  
 0.536
CAJ68871.1
Putative decarboxylase; Experimentally verified through RNA-seq as part of Spo0A regulated transcriptome: down-regulated in Spo0A mutant. Experimentally verified through Mass Spectrometry as part of Spo0A regulated proteome: down-regulated in Spo0A mutant PMID:24568651.
  
 
  0.536
scoA
Succinyl CoA:3-oxoacid CoA-transferase subunit A.
 
  
 0.515
SleB
Putative spore cortex-lytic hydrolase; Experimentally verified through RNA-seq as part of Spo0A regulated transcriptome: down-regulated in Spo0A mutant PMID:24568651.
   
  
 0.505
Your Current Organism:
Clostridioides difficile
NCBI taxonomy Id: 272563
Other names: C. difficile 630, Clostridioides difficile 630, Clostridium difficile 630, Clostridium difficile 630 (epidemic type X), Clostridium difficile str. 630, Clostridium difficile strain 630, Peptoclostridium difficile 630
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