Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
CAJ70020.1PTS system, beta-glucoside-like IIBC component. (466 aa)    
Predicted Functional Partners:
CAJ69398.1
PTS system, glucose-like IIA component.
 
 
 0.969
CAJ69920.1
PTS system, glucose-like IIA component.
 
 
 0.967
CAJ69995.1
PTS system, glucose-like IIA component.
 
 
 0.967
ptsG-A
PTS system, glucose-specific IIA component; Experimentally verified through RNA-seq as part of Spo0A regulated transcriptome: down-regulated in Spo0A mutant PMID:24568651.
 
 
 0.964
ptsH
PTS system, HPr protein.
  
 
 0.928
scrB
Sucrose-6-phosphate hydrolase (Sucrase) (Invertase); Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family.
  
 0.884
bglG3
Transcription antiterminator, PTS operon regulator, bglG3.
 
 0.882
bglG1
Transcription antiterminator, PTS operon regulator, bglG1.
 
 0.809
CAJ68449.2
Transcriptional regulator, repressor ROK family.
  
 
 0.793
cwp24
Putative cell wall-binding protein cwp24.
  
 
 0.793
Your Current Organism:
Clostridioides difficile
NCBI taxonomy Id: 272563
Other names: C. difficile 630, Clostridioides difficile 630, Clostridium difficile 630, Clostridium difficile 630 (epidemic type X), Clostridium difficile str. 630, Clostridium difficile strain 630, Peptoclostridium difficile 630
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