Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
CAJ70099.1Two-component sensor histidine kinase. (376 aa)    
Predicted Functional Partners:
CAJ70100.1
Two-component response regulator.
 
 
 0.955
CAJ67315.1
Two-component response regulator.
 
 
 0.781
CAJ67190.1
Two-component response regulator,Tn916-like,CTn1-Orf13.
 
 
 0.753
CAJ67475.1
Two-component response regulator.
 
 
 0.751
CAJ69609.1
Two-component response regulator.
 
 
 0.739
CAJ68999.1
Two-component response regulator.
 
 
 0.730
CAJ67314.1
Two-component sensor histidine kinase.
 
 
 
 0.729
cheY
Chemotaxis protein CheY.
 
 
 0.721
CAJ70507.1
Two-component response regulator, CheY family.
 
 
 0.720
spaR
Two-component response regulator.
 
 
 0.700
Your Current Organism:
Clostridioides difficile
NCBI taxonomy Id: 272563
Other names: C. difficile 630, Clostridioides difficile 630, Clostridium difficile 630, Clostridium difficile 630 (epidemic type X), Clostridium difficile str. 630, Clostridium difficile strain 630, Peptoclostridium difficile 630
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