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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAJ70099.1Two-component sensor histidine kinase. (376 aa)    
Predicted Functional Partners:
CAJ70100.1
Two-component response regulator.
 
 0.957
CAJ67315.1
Two-component response regulator.
 
 0.790
CAJ67475.1
Two-component response regulator.
 
 0.774
CAJ67190.1
Two-component response regulator,Tn916-like,CTn1-Orf13.
 
 0.764
CAJ69609.1
Two-component response regulator.
 
 0.763
CAJ70507.1
Two-component response regulator, CheY family.
 
 0.746
CAJ68999.1
Two-component response regulator.
 
 0.741
CAJ67314.1
Two-component sensor histidine kinase.
 
 
 0.740
cheY
Chemotaxis protein CheY.
 
 
 0.735
CAJ67142.1
Two-component response regulator.
 
 0.720
Your Current Organism:
Clostridioides difficile
NCBI taxonomy Id: 272563
Other names: C. difficile 630, Clostridioides difficile 630, Clostridium difficile 630, Clostridium difficile 630 (epidemic type X), Clostridium difficile str. 630, Clostridium difficile strain 630, Peptoclostridium difficile 630
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