STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAJ70100.1Two-component response regulator. (223 aa)    
Predicted Functional Partners:
CAJ70099.1
Two-component sensor histidine kinase.
 
 0.957
CAJ69379.1
Two-component sensor histidine kinase,sporulation-associated spo0A.
 
 0.864
CAJ67476.1
Two-component sensor histidine kinase.
 
 0.857
CAJ68443.1
Two-component sensor histidine kinase,sporulation-associated spo0A; Experimentally verified through RNA-seq as part of Spo0A regulated transcriptome: up-regulated in Spo0A mutant. Experimentally verified through Mass Spectrometry as part of Spo0A regulated proteome: up-regulated in Spo0A mutant PMID:24568651.
   0.824
CAJ69422.2
Two-component sensor histidine kinase.
   0.817
CAJ67855.1
Two-component sensor histidine kinase.
 
 0.806
CAJ69523.1
Two-component sensor histidine kinase.
 
 0.796
CAJ70506.1
Two-component sensor histidine kinase.
 
 0.792
CAJ70163.1
Two-component sensor histidine kinase.
 
   0.778
CAJ68831.1
Two-component sensor histidine kinase.
 
 0.777
Your Current Organism:
Clostridioides difficile
NCBI taxonomy Id: 272563
Other names: C. difficile 630, Clostridioides difficile 630, Clostridium difficile 630, Clostridium difficile 630 (epidemic type X), Clostridium difficile str. 630, Clostridium difficile strain 630, Peptoclostridium difficile 630
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.