STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hupANon-specific DNA-binding protein HBsu; Experimentally verified as part of mature spore proteome PMID:19542279; Belongs to the bacterial histone-like protein family. (92 aa)    
Predicted Functional Partners:
CAJ70399.2
Putative RNA-binding S4 domain-containing protein.
 
    0.843
CAJ70397.1
Putative membrane protein.
  
    0.798
pheA
Bifunctional P-protein, chorismate mutase/prephenate dehydratase.
  
  
 0.721
YabN
Bifunctional protein [Includes: Tetrapyrrole methylase; NTP pyrophosphohydrolase MazG].
  
  
 0.694
rpsT
30S ribosomal protein S20; Binds directly to 16S ribosomal RNA.
  
  
 0.674
rpsO
30S ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
  
  
 0.655
polA
DNA polymerase I (POLI); In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
 
 
 0.653
YabP
Putative spore protein.
  
    0.650
mnaA
UDP-N-acetylglucosamine 2-epimerase (UDP-GlcNAc-2-epimerase); Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
   
  
 0.629
metG
Methionyl-tRNA synthetase (Methionine--tRNA ligase) (MetRS); Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
 
 
 0.629
Your Current Organism:
Clostridioides difficile
NCBI taxonomy Id: 272563
Other names: C. difficile 630, Clostridioides difficile 630, Clostridium difficile 630, Clostridium difficile 630 (epidemic type X), Clostridium difficile str. 630, Clostridium difficile strain 630, Peptoclostridium difficile 630
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.