Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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YedFSelenium metabolism protein yedf; Experimentally verified as part of mature spore proteome PMID:19542279; Belongs to the sulfur carrier protein TusA family. (200 aa)    
Predicted Functional Partners:
iscS1
Cysteine desulfurase.
   
 
 0.838
iscS2
Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
   
 
 0.838
selD
Selenide, water dikinase (Selenophosphate synthetase) (Selenium donor protein); Synthesizes selenophosphate from selenide and ATP.
 
   
 0.837
CAJ70575.1
Conserved hypothetical protein.
 
   
 0.806
selB
Selenocysteinyl-tRNA-specific translation factor.
 
  
 0.800
CAJ69254.1
Conserved hypothetical protein.
  
  
 0.798
YjiM
Putative 2-hydroxyacyl-CoA dehydratase.
 
    0.746
selA
L-seryl-tRNA(Sec) selenium transferase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
 
  
 0.726
SufS2
Putative cysteine desulfurase family protein.
 
 
 
 0.669
CAJ68667.1
Coenzyme A disulfide reductase (CoA-disulfide reductase) (CoADR); Experimentally verified through RNA-seq as part of Spo0A regulated transcriptome: up-regulated in Spo0A mutant. Experimentally verified through Mass Spectrometry as part of Spo0A regulated proteome: up-regulated in Spo0A mutant PMID:24568651.
  
  
 0.650
Your Current Organism:
Clostridioides difficile
NCBI taxonomy Id: 272563
Other names: C. difficile 630, Clostridioides difficile 630, Clostridium difficile 630, Clostridium difficile 630 (epidemic type X), Clostridium difficile str. 630, Clostridium difficile strain 630, Peptoclostridium difficile 630
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