STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
spo0JStage 0 sporulation protein J, site-specific DNA-binding protein; Belongs to the ParB family. (287 aa)    
Predicted Functional Partners:
soj
Transcriptional regulator, sporulation initiation inhibitor, chromosome partitioning protein.
 
 0.999
CD630_20080
Fragment of conserved hypothetical protein (N-terminal region).
 
 
 0.967
Noc
Putative stage 0 sporulation protein,DNA-binding protein Spo0J-like; Belongs to the ParB family.
 
   
0.869
ftsK
DNA FtsK/SpoIIIE translocase; Belongs to the FtsK/SpoIIIE/SftA family.
  
  
 0.777
SufS2
Putative cysteine desulfurase family protein.
  
    0.725
CAJ66934.1
Putative atp/gtp-binding protein; Experimentally verified through RNA-seq as part of Spo0A regulated transcriptome: up-regulated in Spo0A mutant PMID:24568651.
  
 
 0.697
polA
DNA polymerase I (POLI); In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
 
  
 0.694
dnaA
Chromosomal replication initiator protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
 
  
 0.660
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
 
 0.616
CAJ70236.1
Putative ATPase Tn916-like, CTn6-Orf15.
    
 
 0.613
Your Current Organism:
Clostridioides difficile
NCBI taxonomy Id: 272563
Other names: C. difficile 630, Clostridioides difficile 630, Clostridium difficile 630, Clostridium difficile 630 (epidemic type X), Clostridium difficile str. 630, Clostridium difficile strain 630, Peptoclostridium difficile 630
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.