node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GDI3341 | glyA | GDI3341 | GDI3012 | Putative threonine dehydratase catabolic. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.890 |
GDI3341 | trpA | GDI3341 | GDI1254 | Putative threonine dehydratase catabolic. | Putative Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.882 |
GDI3341 | trpB | GDI3341 | GDI1255 | Putative threonine dehydratase catabolic. | Putative Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.919 |
GDI3341 | trpC | GDI3341 | GDI1937 | Putative threonine dehydratase catabolic. | Putative indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.650 |
GDI3341 | trpF | GDI3341 | GDI1328 | Putative threonine dehydratase catabolic. | Putative N-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. | 0.591 |
glyA | GDI3341 | GDI3012 | GDI3341 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Putative threonine dehydratase catabolic. | 0.890 |
glyA | trpA | GDI3012 | GDI1254 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Putative Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.955 |
glyA | trpB | GDI3012 | GDI1255 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Putative Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.890 |
glyA | trpC | GDI3012 | GDI1937 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Putative indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.451 |
glyA | trpF | GDI3012 | GDI1328 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Putative N-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. | 0.561 |
lgt | trpA | GDI0929 | GDI1254 | Putative prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | Putative Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.921 |
lgt | trpB | GDI0929 | GDI1255 | Putative prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | Putative Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.912 |
pabB | trpA | GDI1185 | GDI1254 | Putative Para-aminobenzoate synthase. | Putative Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.950 |
pabB | trpB | GDI1185 | GDI1255 | Putative Para-aminobenzoate synthase. | Putative Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.967 |
pabB | trpC | GDI1185 | GDI1937 | Putative Para-aminobenzoate synthase. | Putative indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.999 |
pabB | trpD | GDI1185 | GDI1936 | Putative Para-aminobenzoate synthase. | Putative anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.999 |
pabB | trpE | GDI1185 | GDI1934 | Putative Para-aminobenzoate synthase. | Anthranilate synthase component 1; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.877 |
pabB | trpF | GDI1185 | GDI1328 | Putative Para-aminobenzoate synthase. | Putative N-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. | 0.980 |
pabB | trpG | GDI1185 | GDI1935 | Putative Para-aminobenzoate synthase. | Putative mnthranilate synthase component 2. | 0.999 |
trpA | GDI3341 | GDI1254 | GDI3341 | Putative Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | Putative threonine dehydratase catabolic. | 0.882 |