| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| GDI1503 | GDI1992 | GDI1503 | GDI1992 | Dihydroorotate dehydrogenase. | Conserved hypothetical protein. | 0.488 |
| GDI1503 | deoD | GDI1503 | GDI2055 | Dihydroorotate dehydrogenase. | 5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | 0.895 |
| GDI1503 | guaD | GDI1503 | GDI1732 | Dihydroorotate dehydrogenase. | Putative guanine deaminase. | 0.810 |
| GDI1503 | nsnH | GDI1503 | GDI1251 | Dihydroorotate dehydrogenase. | Putative Inosine-uridine preferring nucleoside hydrolase. | 0.420 |
| GDI1503 | rih | GDI1503 | GDI2387 | Dihydroorotate dehydrogenase. | Putative pyrimidine-specific ribonucleoside hydrolase. | 0.420 |
| GDI1992 | GDI1503 | GDI1992 | GDI1503 | Conserved hypothetical protein. | Dihydroorotate dehydrogenase. | 0.488 |
| GDI1992 | guaD | GDI1992 | GDI1732 | Conserved hypothetical protein. | Putative guanine deaminase. | 0.674 |
| GDI1992 | xdhA | GDI1992 | GDI2003 | Conserved hypothetical protein. | Putative xanthine dehydrogenase, xdhA. | 0.844 |
| GDI1992 | xdhB | GDI1992 | GDI2002 | Conserved hypothetical protein. | Putative xanthine dehydrogenase/oxidase. | 0.884 |
| GDI2982 | guaD | GDI2982 | GDI1732 | Putative N-formylglutamate amidohydrolase. | Putative guanine deaminase. | 0.732 |
| apt | deoD | GDI1344 | GDI2055 | Putative adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | 0.979 |
| apt | guaD | GDI1344 | GDI1732 | Putative adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Putative guanine deaminase. | 0.757 |
| apt | nsnH | GDI1344 | GDI1251 | Putative adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Putative Inosine-uridine preferring nucleoside hydrolase. | 0.865 |
| apt | rih | GDI1344 | GDI2387 | Putative adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Putative pyrimidine-specific ribonucleoside hydrolase. | 0.846 |
| deoD | GDI1503 | GDI2055 | GDI1503 | 5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | Dihydroorotate dehydrogenase. | 0.895 |
| deoD | apt | GDI2055 | GDI1344 | 5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | Putative adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.979 |
| deoD | guaD | GDI2055 | GDI1732 | 5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | Putative guanine deaminase. | 0.773 |
| deoD | nsnH | GDI2055 | GDI1251 | 5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | Putative Inosine-uridine preferring nucleoside hydrolase. | 0.540 |
| deoD | rih | GDI2055 | GDI2387 | 5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | Putative pyrimidine-specific ribonucleoside hydrolase. | 0.540 |
| deoD | spe | GDI2055 | GDI2319 | 5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine; Belongs to the spermidine/spermine synthase family. | 0.933 |