| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| GDI1962 | grpE | GDI1962 | GDI1263 | Putative monothiol glutaredoxin; Belongs to the glutaredoxin family. Monothiol subfamily. | Chaperone binding; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | 0.529 |
| GDI1962 | ubiA | GDI1962 | GDI3252 | Putative monothiol glutaredoxin; Belongs to the glutaredoxin family. Monothiol subfamily. | Putative 4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.917 |
| GDI1962 | ubiG | GDI1962 | GDI1908 | Putative monothiol glutaredoxin; Belongs to the glutaredoxin family. Monothiol subfamily. | 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.644 |
| GDI1962 | ubiH | GDI1962 | GDI2350 | Putative monothiol glutaredoxin; Belongs to the glutaredoxin family. Monothiol subfamily. | 2-octaprenyl-6-methoxyphenol hydroxylase. | 0.523 |
| GDI3251 | GDI3253 | GDI3251 | GDI3253 | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | Conserved hypothetical protein. | 0.644 |
| GDI3251 | ubiA | GDI3251 | GDI3252 | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | Putative 4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.700 |
| GDI3253 | GDI3251 | GDI3253 | GDI3251 | Conserved hypothetical protein. | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | 0.644 |
| GDI3253 | ubiA | GDI3253 | GDI3252 | Conserved hypothetical protein. | Putative 4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.841 |
| etfD | ispA | GDI1278 | GDI1861 | Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. | Geranyltranstransferase; Belongs to the FPP/GGPP synthase family. | 0.516 |
| etfD | ispB | GDI1278 | GDI1826 | Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. | Putative octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 0.516 |
| etfD | ubiA | GDI1278 | GDI3252 | Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. | Putative 4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.619 |
| etfD | ubiG | GDI1278 | GDI1908 | Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. | 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.585 |
| grpE | GDI1962 | GDI1263 | GDI1962 | Chaperone binding; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | Putative monothiol glutaredoxin; Belongs to the glutaredoxin family. Monothiol subfamily. | 0.529 |
| grpE | ubiA | GDI1263 | GDI3252 | Chaperone binding; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | Putative 4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.576 |
| ispA | etfD | GDI1861 | GDI1278 | Geranyltranstransferase; Belongs to the FPP/GGPP synthase family. | Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. | 0.516 |
| ispA | ispB | GDI1861 | GDI1826 | Geranyltranstransferase; Belongs to the FPP/GGPP synthase family. | Putative octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 0.803 |
| ispA | ubiA | GDI1861 | GDI3252 | Geranyltranstransferase; Belongs to the FPP/GGPP synthase family. | Putative 4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.665 |
| ispA | ubiE-2 | GDI1861 | GDI1768 | Geranyltranstransferase; Belongs to the FPP/GGPP synthase family. | Ubiquinone/menaquinone biosynthesis methyltransferase ubi; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.540 |
| ispB | etfD | GDI1826 | GDI1278 | Putative octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. | 0.516 |
| ispB | ispA | GDI1826 | GDI1861 | Putative octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | Geranyltranstransferase; Belongs to the FPP/GGPP synthase family. | 0.803 |