| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| GDI3322 | GDI3323 | GDI3322 | GDI3323 | Conserved hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Conserved hypothetical protein. | 0.664 |
| GDI3322 | GDI3324 | GDI3322 | GDI3324 | Conserved hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Putative D-lactate dehydrogenase. | 0.593 |
| GDI3322 | cysQ | GDI3322 | GDI3321 | Conserved hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Inositol monophosphatase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. | 0.972 |
| GDI3322 | glmS | GDI3322 | GDI1778 | Conserved hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 3.1.0; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.468 |
| GDI3322 | glyA | GDI3322 | GDI3012 | Conserved hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.792 |
| GDI3322 | ksgA | GDI3322 | GDI3329 | Conserved hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Putative dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.580 |
| GDI3322 | pepA-2 | GDI3322 | GDI3320 | Conserved hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Cytosol aminopeptidase protein; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. | 0.580 |
| GDI3322 | polA | GDI3322 | GDI3537 | Conserved hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Putative DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.503 |
| GDI3322 | surA | GDI3322 | GDI3328 | Conserved hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Peptidyl-prolyl cis-trans isomerase SurA. | 0.475 |
| GDI3322 | tsaD | GDI3322 | GDI2071 | Conserved hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Putative O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.750 |
| GDI3323 | GDI3322 | GDI3323 | GDI3322 | Conserved hypothetical protein. | Conserved hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 0.664 |
| GDI3323 | GDI3324 | GDI3323 | GDI3324 | Conserved hypothetical protein. | Putative D-lactate dehydrogenase. | 0.678 |
| GDI3323 | cysQ | GDI3323 | GDI3321 | Conserved hypothetical protein. | Inositol monophosphatase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. | 0.627 |
| GDI3323 | ksgA | GDI3323 | GDI3329 | Conserved hypothetical protein. | Putative dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.412 |
| GDI3323 | pepA-2 | GDI3323 | GDI3320 | Conserved hypothetical protein. | Cytosol aminopeptidase protein; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. | 0.451 |
| GDI3323 | surA | GDI3323 | GDI3328 | Conserved hypothetical protein. | Peptidyl-prolyl cis-trans isomerase SurA. | 0.492 |
| GDI3324 | GDI3322 | GDI3324 | GDI3322 | Putative D-lactate dehydrogenase. | Conserved hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 0.593 |
| GDI3324 | GDI3323 | GDI3324 | GDI3323 | Putative D-lactate dehydrogenase. | Conserved hypothetical protein. | 0.678 |
| GDI3324 | cysQ | GDI3324 | GDI3321 | Putative D-lactate dehydrogenase. | Inositol monophosphatase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. | 0.546 |
| GDI3324 | glyA | GDI3324 | GDI3012 | Putative D-lactate dehydrogenase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.467 |