| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| GDI3836 | guaA | GDI3836 | GDI3147 | Conserved hypothetical protein. | Gmp synthase [glutamine-hydrolyzing] (glutamin amidotransferase) (gmp synthetase); Catalyzes the synthesis of GMP from XMP. | 0.959 |
| GDI3836 | guaB | GDI3836 | GDI1811 | Conserved hypothetical protein. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.884 |
| GDI3836 | kdsD | GDI3836 | GDI2115 | Conserved hypothetical protein. | Putative arabinose 5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.852 |
| GDI3836 | metH | GDI3836 | GDI3502 | Conserved hypothetical protein. | Putative methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.846 |
| GDI3836 | pykA | GDI3836 | GDI1290 | Conserved hypothetical protein. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.850 |
| GDI3836 | rplC | GDI3836 | GDI3404 | Conserved hypothetical protein. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.834 |
| GDI3836 | rplN | GDI3836 | GDI3394 | Conserved hypothetical protein. | Putative 50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. | 0.830 |
| GDI3836 | rpsB | GDI3836 | GDI3020 | Conserved hypothetical protein. | 30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 0.829 |
| GDI3836 | rpsD | GDI3836 | GDI2196 | Conserved hypothetical protein. | 30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 0.831 |
| GDI3836 | rpsJ | GDI3836 | GDI3405 | Conserved hypothetical protein. | Putative 30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.831 |
| guaA | GDI3836 | GDI3147 | GDI3836 | Gmp synthase [glutamine-hydrolyzing] (glutamin amidotransferase) (gmp synthetase); Catalyzes the synthesis of GMP from XMP. | Conserved hypothetical protein. | 0.959 |
| guaA | guaB | GDI3147 | GDI1811 | Gmp synthase [glutamine-hydrolyzing] (glutamin amidotransferase) (gmp synthetase); Catalyzes the synthesis of GMP from XMP. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.999 |
| guaA | kdsD | GDI3147 | GDI2115 | Gmp synthase [glutamine-hydrolyzing] (glutamin amidotransferase) (gmp synthetase); Catalyzes the synthesis of GMP from XMP. | Putative arabinose 5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.925 |
| guaA | pykA | GDI3147 | GDI1290 | Gmp synthase [glutamine-hydrolyzing] (glutamin amidotransferase) (gmp synthetase); Catalyzes the synthesis of GMP from XMP. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.622 |
| guaA | rplC | GDI3147 | GDI3404 | Gmp synthase [glutamine-hydrolyzing] (glutamin amidotransferase) (gmp synthetase); Catalyzes the synthesis of GMP from XMP. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.797 |
| guaA | rplN | GDI3147 | GDI3394 | Gmp synthase [glutamine-hydrolyzing] (glutamin amidotransferase) (gmp synthetase); Catalyzes the synthesis of GMP from XMP. | Putative 50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. | 0.649 |
| guaA | rpsB | GDI3147 | GDI3020 | Gmp synthase [glutamine-hydrolyzing] (glutamin amidotransferase) (gmp synthetase); Catalyzes the synthesis of GMP from XMP. | 30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 0.680 |
| guaA | rpsD | GDI3147 | GDI2196 | Gmp synthase [glutamine-hydrolyzing] (glutamin amidotransferase) (gmp synthetase); Catalyzes the synthesis of GMP from XMP. | 30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 0.882 |
| guaA | rpsJ | GDI3147 | GDI3405 | Gmp synthase [glutamine-hydrolyzing] (glutamin amidotransferase) (gmp synthetase); Catalyzes the synthesis of GMP from XMP. | Putative 30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.686 |
| guaB | GDI3836 | GDI1811 | GDI3836 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Conserved hypothetical protein. | 0.884 |