STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fbp2Fructose-16-bisphosphatase. (291 aa)    
Predicted Functional Partners:
fba
Fructose-bisphosphate aldolase.
    
 0.951
pgi
Glucose-6-phosphate isomerase.
   
 
 0.931
deoC2
Deoxyribose-phosphate aldolase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
    
 0.925
pfk4
1-phosphofructokinase.
    
 0.924
fbp1
Fructose-16-bisphosphatase.
  
  
 
0.904
icd
Isocitrate dehydrogenase.
   
  
 0.667
mdh
L-malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily.
   
 
 0.621
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
   
  
 0.582
gapB
Glyceraldehyde 3-phosphate dehydrogenase.
  
  
 0.558
gapA
Glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
  
 0.558
Your Current Organism:
Haloarcula marismortui
NCBI taxonomy Id: 272569
Other names: H. marismortui ATCC 43049, Haloarcula marismortui ATCC 43049, Haloarcula marismortui str. ATCC 43049, Haloarcula marismortui strain ATCC 43049
Server load: low (38%) [HD]