| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cbiA2 | cbiC | rrnAC1102 | rrnAC3020 | Cobyrinic acid ac-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | precorrin-8X methylmutase. | 0.995 |
| cbiA2 | cbiF | rrnAC1102 | rrnAC3001 | Cobyrinic acid ac-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Cobalamin biosynthesis precorrin-3 methylase. | 0.930 |
| cbiA2 | cbiG | rrnAC1102 | rrnAC3003 | Cobyrinic acid ac-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Cobalamin biosynthesis protein G. | 0.941 |
| cbiA2 | cbiL | rrnAC1102 | rrnAC3000 | Cobyrinic acid ac-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.944 |
| cbiA2 | cbiT | rrnAC1102 | rrnAC2998 | Cobyrinic acid ac-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | precorrin-8W decarboxylase. | 0.877 |
| cbiA2 | cobQ | rrnAC1102 | rrnAC1938 | Cobyrinic acid ac-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.986 |
| cbiA2 | cobS | rrnAC1102 | rrnAC1931 | Cobyrinic acid ac-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Cobalamin-5-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.765 |
| cbiA2 | hisC1 | rrnAC1102 | rrnAC1934 | Cobyrinic acid ac-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Histidinol-phosphate aminotransferase. | 0.958 |
| cbiA2 | rrnAC1101 | rrnAC1102 | rrnAC1101 | Cobyrinic acid ac-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Unknown; Belongs to the UPF0284 family. | 0.971 |
| cbiA2 | rrnAC1930 | rrnAC1102 | rrnAC1930 | Cobyrinic acid ac-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Putative CobD/Cbib protein. | 0.897 |
| cbiC | cbiA2 | rrnAC3020 | rrnAC1102 | precorrin-8X methylmutase. | Cobyrinic acid ac-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.995 |
| cbiC | cbiF | rrnAC3020 | rrnAC3001 | precorrin-8X methylmutase. | Cobalamin biosynthesis precorrin-3 methylase. | 0.994 |
| cbiC | cbiG | rrnAC3020 | rrnAC3003 | precorrin-8X methylmutase. | Cobalamin biosynthesis protein G. | 0.982 |
| cbiC | cbiL | rrnAC3020 | rrnAC3000 | precorrin-8X methylmutase. | Precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.996 |
| cbiC | cbiT | rrnAC3020 | rrnAC2998 | precorrin-8X methylmutase. | precorrin-8W decarboxylase. | 0.992 |
| cbiC | cobQ | rrnAC3020 | rrnAC1938 | precorrin-8X methylmutase. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.992 |
| cbiC | cobS | rrnAC3020 | rrnAC1931 | precorrin-8X methylmutase. | Cobalamin-5-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.876 |
| cbiC | hisC1 | rrnAC3020 | rrnAC1934 | precorrin-8X methylmutase. | Histidinol-phosphate aminotransferase. | 0.512 |
| cbiC | rrnAC1101 | rrnAC3020 | rrnAC1101 | precorrin-8X methylmutase. | Unknown; Belongs to the UPF0284 family. | 0.815 |
| cbiC | rrnAC1930 | rrnAC3020 | rrnAC1930 | precorrin-8X methylmutase. | Putative CobD/Cbib protein. | 0.923 |