STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mcm1MCM / cell division control protein 21; Belongs to the MCM family. (681 aa)    
Predicted Functional Partners:
polB1
DNA polymerase B elongation subunit.
  
 0.965
cdc6b
Cell division control protein 6 homolog 1; Involved in regulation of DNA replication.
 
 0.921
cdc6d
Cell division control protein 6-like; Involved in regulation of DNA replication.
 
 0.907
cdc6g
Cell division control protein 6; Involved in regulation of DNA replication.
 
 0.906
pri2
Eukaryotic-type DNA primase large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.
  
 
 0.905
mcm2
Cell division control protein 21.
 
  
 
0.904
cdc6a
Cell division control protein 6 homolog 1; Involved in regulation of DNA replication.
 
 0.903
cdc6e
Orc / cell division control protein 6.
 
 0.898
cdc6h
Cell division control protein 6 homolog 2; Involved in regulation of DNA replication.
 
 0.897
cdc6i
Cell division control protein 6 homolog 6; Involved in regulation of DNA replication.
 
 0.895
Your Current Organism:
Haloarcula marismortui
NCBI taxonomy Id: 272569
Other names: H. marismortui ATCC 43049, Haloarcula marismortui ATCC 43049, Haloarcula marismortui str. ATCC 43049, Haloarcula marismortui strain ATCC 43049
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.