STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
citZCitrate synthase II. (381 aa)    
Predicted Functional Partners:
acnB
Aconitate hydratase.
  
 0.999
icd
Isocitrate dehydrogenase.
 
 
 0.999
mdh
L-malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily.
  
 0.998
sucC
succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.991
sdhB
Succinate dehydrogenase iron-sulfur protein subunit.
  
 
 0.983
pdhC2
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
  
 0.981
pdhC1
Dihydrolipoamide S-acetyltransferase component of pyruvate dehydrogenase complex E2.
  
 0.981
acs1
Acyl-coenzyme A synthetases.
  
 0.974
acs
Unknown.
  
 0.974
acs5
Putative acetyl-coenzyme A synthetase.
  
 0.974
Your Current Organism:
Haloarcula marismortui
NCBI taxonomy Id: 272569
Other names: H. marismortui ATCC 43049, Haloarcula marismortui ATCC 43049, Haloarcula marismortui str. ATCC 43049, Haloarcula marismortui strain ATCC 43049
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.