STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
polA2DNA polymerase II large subunit; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase (By similarity). (1395 aa)    
Predicted Functional Partners:
polA1
DNA polymerase II small subunit; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase; Belongs to the DNA polymerase delta/II small subunit family.
 
 
 
 0.992
pcnA
DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family.
 
 
 
 0.963
rrnAC2689
Unknown.
       0.872
cdc6d
Cell division control protein 6-like; Involved in regulation of DNA replication.
 
   
 0.849
cdc6e
Orc / cell division control protein 6.
 
   
 0.837
cdc6a
Cell division control protein 6 homolog 1; Involved in regulation of DNA replication.
 
   
 0.824
recJ5
RecJ-like exonuclease; DHH/DHHA1 family protein.
 
     0.733
rrnAC3510
Unknown.
  
     0.728
nac-2
Unknown; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family.
  
     0.727
nusG
Transcription antitermination protein NusG; Stimulates transcription elongation; Belongs to the archaeal Spt5 family.
  
     0.714
Your Current Organism:
Haloarcula marismortui
NCBI taxonomy Id: 272569
Other names: H. marismortui ATCC 43049, Haloarcula marismortui ATCC 43049, Haloarcula marismortui str. ATCC 43049, Haloarcula marismortui strain ATCC 43049
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.