STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
apt1Adenine phosphoribosyltransferase; May catalyze a purine salvage reaction, the substrate is unknown. (189 aa)    
Predicted Functional Partners:
guaA1
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
 0.981
purH
Bifunctional purine biosynthesis protein PurH; Includes phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (AICAR transformylase) and IMP cyclohydrolase.
  
 0.966
purB
Adenylosuccinate lyase.
  
 0.961
adk-2
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
  
 
 0.944
guaA2
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
 
 0.938
guaA3
GMP synthase; Glutamine-hydrolyzing.
  
 
 0.938
guaA4
GMP synthase.
  
 
 0.938
surE
Acid phosphatase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
 0.922
iunH2
Inosine-uridine preferring nucleoside hydrolase.
    
 0.919
rrnAC0531
Unknown.
   
 
  0.907
Your Current Organism:
Haloarcula marismortui
NCBI taxonomy Id: 272569
Other names: H. marismortui ATCC 43049, Haloarcula marismortui ATCC 43049, Haloarcula marismortui str. ATCC 43049, Haloarcula marismortui strain ATCC 43049
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