node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KPN_00325 | yaiB | KPN_00325 | KPN_00326 | Putative permease. | Hypothetical protein; Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS especially during phosphate starvation, but also in stationary phase and during nitrogen starvation. Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway. | 0.421 |
KPN_04490 | arcB | KPN_04490 | KPN_03619 | Putative histidine protein kinase. | Aerobic respiration sensor-response protein; histidine protein kinase/phosphatase, sensor for arcA. | 0.999 |
KPN_04490 | barA | KPN_04490 | KPN_03128 | Putative histidine protein kinase. | Hybrid sensory histidine kinase in two-component regulatory system with UvrY. | 0.998 |
KPN_04490 | evgS | KPN_04490 | KPN_03481 | Putative histidine protein kinase. | Putative sensor protein EvgS1. | 0.998 |
KPN_04490 | rcsC | KPN_04490 | KPN_02639 | Putative histidine protein kinase. | Hybrid sensory histidine kinase in two-component regulatory system with RcsB; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB. | 0.875 |
KPN_04490 | yaiB | KPN_04490 | KPN_00326 | Putative histidine protein kinase. | Hypothetical protein; Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS especially during phosphate starvation, but also in stationary phase and during nitrogen starvation. Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway. | 0.420 |
arcB | KPN_04490 | KPN_03619 | KPN_04490 | Aerobic respiration sensor-response protein; histidine protein kinase/phosphatase, sensor for arcA. | Putative histidine protein kinase. | 0.999 |
arcB | barA | KPN_03619 | KPN_03128 | Aerobic respiration sensor-response protein; histidine protein kinase/phosphatase, sensor for arcA. | Hybrid sensory histidine kinase in two-component regulatory system with UvrY. | 0.999 |
arcB | evgS | KPN_03619 | KPN_03481 | Aerobic respiration sensor-response protein; histidine protein kinase/phosphatase, sensor for arcA. | Putative sensor protein EvgS1. | 0.999 |
arcB | hnr | KPN_03619 | KPN_02203 | Aerobic respiration sensor-response protein; histidine protein kinase/phosphatase, sensor for arcA. | Hnr protein; Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co- degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation. | 0.997 |
arcB | rcsC | KPN_03619 | KPN_02639 | Aerobic respiration sensor-response protein; histidine protein kinase/phosphatase, sensor for arcA. | Hybrid sensory histidine kinase in two-component regulatory system with RcsB; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB. | 0.999 |
arcB | rpoS | KPN_03619 | KPN_03103 | Aerobic respiration sensor-response protein; histidine protein kinase/phosphatase, sensor for arcA. | RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response. | 0.581 |
arcB | yaiB | KPN_03619 | KPN_00326 | Aerobic respiration sensor-response protein; histidine protein kinase/phosphatase, sensor for arcA. | Hypothetical protein; Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS especially during phosphate starvation, but also in stationary phase and during nitrogen starvation. Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway. | 0.423 |
barA | KPN_04490 | KPN_03128 | KPN_04490 | Hybrid sensory histidine kinase in two-component regulatory system with UvrY. | Putative histidine protein kinase. | 0.998 |
barA | arcB | KPN_03128 | KPN_03619 | Hybrid sensory histidine kinase in two-component regulatory system with UvrY. | Aerobic respiration sensor-response protein; histidine protein kinase/phosphatase, sensor for arcA. | 0.999 |
barA | evgS | KPN_03128 | KPN_03481 | Hybrid sensory histidine kinase in two-component regulatory system with UvrY. | Putative sensor protein EvgS1. | 0.999 |
barA | hnr | KPN_03128 | KPN_02203 | Hybrid sensory histidine kinase in two-component regulatory system with UvrY. | Hnr protein; Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co- degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation. | 0.956 |
barA | rcsC | KPN_03128 | KPN_02639 | Hybrid sensory histidine kinase in two-component regulatory system with UvrY. | Hybrid sensory histidine kinase in two-component regulatory system with RcsB; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB. | 0.998 |
barA | rpoS | KPN_03128 | KPN_03103 | Hybrid sensory histidine kinase in two-component regulatory system with UvrY. | RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response. | 0.514 |
barA | yaiB | KPN_03128 | KPN_00326 | Hybrid sensory histidine kinase in two-component regulatory system with UvrY. | Hypothetical protein; Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS especially during phosphate starvation, but also in stationary phase and during nitrogen starvation. Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway. | 0.421 |