Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
rpoERNA polymerase delta subunit; Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; Belongs to the RpoE family. (184 aa)    
Predicted Functional Partners:
LBA0230
Hypothetical protein; COG1078 HD family phosphohydrolases.
 
     0.810
LBA0420
Hypothetical protein; Belongs to the UPF0473 family.
  
     0.743
pyrG
CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
  
    0.732
LBA0231
Hypothetical protein.
  
    0.713
LBA0829
Hypothetical protein; Belongs to the UPF0356 family.
  
  
 0.698
LBA0384
Hypothetical protein; Involved in initiation control of chromosome replication. Belongs to the YabA family.
  
     0.693
LBA0428
COG4768 Uncharacterized protein containing a divergent version of the methyl-accepting chemotaxis-like domain.
  
     0.686
LBA0270
Hypothetical protein; COG0517 FOG CBS domain putative.
 
     0.680
LBA0435
Hypothetical protein.
  
     0.670
LBA1531
GTP-binding protein; COG1161 Predicted GTPases.
 
    0.609
Your Current Organism:
Lactobacillus acidophilus
NCBI taxonomy Id: 272621
Other names: L. acidophilus NCFM, Lactobacillus acidophilus NCFM, Lactobacillus acidophilus str. NCFM, Lactobacillus acidophilus strain NCFM
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