STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (397 aa)    
Predicted Functional Partners:
EutD
Phosphate acetyltransferase; COG0280 Phosphotransacetylase.
 
 0.988
poxB
Pyruvate oxidase; COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome); Belongs to the TPP enzyme family.
    
 0.957
adhE
COG1012 NAD-dependent aldehyde dehydrogenases; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
  
 0.742
LBA0600
Xylulose-5-phosphate-fructose phosphoketolase.
 
  
 0.677
pgk
COG0126 3-phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
  
  
 0.624
ccpA
Catabolite control protein A; pepR1.
   
 
 0.602
fabG
3-oxoacyl-(acyl-carrier protein) reductase; FabG.
  
  
 0.573
LBA1075
Malolactic enzyme.
     
 0.572
LBA0464
Putative carboxymuconolactone decarboxylase.
       0.562
pyrD
Dihydroorotate dehydrogenase B, catalytic unit; Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
     
 0.481
Your Current Organism:
Lactobacillus acidophilus
NCBI taxonomy Id: 272621
Other names: L. acidophilus NCFM, Lactobacillus acidophilus NCFM, Lactobacillus acidophilus str. NCFM, Lactobacillus acidophilus strain NCFM
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.