STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ppcPhosphoenolpyruvate carboxylase Ppc; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (912 aa)    
Predicted Functional Partners:
kpyK
Pyruvate kinase; COG3848 Phosphohistidine swiveling domain; Belongs to the pyruvate kinase family.
     
 0.936
eno
2-phosphoglycerate dehydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 
 0.935
LBA0466
Hypothetical protein.
     
 0.929
pepD
Aminoacyl-histidine dipeptidase; PepD; carnosinase.
  
  
 0.666
pepP
X-Pro dipeptidase; COG0006 Xaa-Pro aminopeptidase.
  
  
 0.646
tpiA
Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
  
 0.610
pepN
Aminopeptidase N.
     
 0.596
pepF
Oligopeptidase; Endopeptidase F.
     
 0.593
metK
Putative methionine synthase; MetE.
  
  
 0.586
LBA1695
Aspartate aminotransferase.
     
 0.578
Your Current Organism:
Lactobacillus acidophilus
NCBI taxonomy Id: 272621
Other names: L. acidophilus NCFM, Lactobacillus acidophilus NCFM, Lactobacillus acidophilus str. NCFM, Lactobacillus acidophilus strain NCFM
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.