STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (287 aa)    
Predicted Functional Partners:
thrC
ThrC; COG0498 Threonine synthase.
 
 0.999
LBA1212
Homoserine dehydrogenase Hdh.
 
 0.998
LBA1215
Aspartokinase; ThrA2; COG0527 Aspartokinases; Belongs to the aspartokinase family.
 
 
 0.974
LBA0850
COG0527 Aspartokinases; Belongs to the aspartokinase family.
 
 
 0.945
purM
Phosphoribosylformylglycinamide cyclo-ligase; PurM; phosphoribosylaminoimidazole synthetase.
    
 0.913
ilvE
IlvE; COG0115 Branched-chain amino acid aminotransferase-4-amino-4-deoxychorismate lyase.
  
 
 0.870
metA
Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-serine, forming acetyl-L-serine; Belongs to the MetA family.
 
  
 0.868
LBA1089
Cystathionine beta-lyase; Potential frameshift to 1090.
  
 
 0.854
metC
Cystathionine beta-lyase; Potential frameshift to 1089; MetC.
  
 
 0.854
sdhB
L-serine dehydratase, beta subunit.
  
 
 0.848
Your Current Organism:
Lactobacillus acidophilus
NCBI taxonomy Id: 272621
Other names: L. acidophilus NCFM, Lactobacillus acidophilus NCFM, Lactobacillus acidophilus str. NCFM, Lactobacillus acidophilus strain NCFM
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.