STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LBA1279COG4224 Uncharacterized protein conserved in bacteria. (86 aa)    
Predicted Functional Partners:
LBA1278
Hypothetical protein.
 
    0.899
lexA
Transcriptional repressor protein; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
  
  
 0.801
LBA0420
Hypothetical protein; Belongs to the UPF0473 family.
  
   
 0.521
ezrA
Cell division regulator; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family.
  
     0.501
LBA0740
Putative modification methylase; COG0827 Adenine-specific DNA methylase.
  
     0.499
LBA0419
Hypothetical protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family.
  
    0.465
LBA1277
ABC transporter ATP binding and permease protein.
       0.465
ftsQ
Cell division protein; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily.
 
     0.458
arsC
Putative arsenate reductase; Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development- promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress. Belongs to the ArsC family. Spx subfamily.
  
     0.448
LBA0971
Putative O-linked transferase; GlcNAc; hypothetical protein.
  
     0.435
Your Current Organism:
Lactobacillus acidophilus
NCBI taxonomy Id: 272621
Other names: L. acidophilus NCFM, Lactobacillus acidophilus NCFM, Lactobacillus acidophilus str. NCFM, Lactobacillus acidophilus strain NCFM
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.