STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pbpX-2Putative penicillin-binding protein. (343 aa)    
Predicted Functional Partners:
dltB
Membrane protein; Could be involved in the transport of activated D-alanine through the membrane.
 
  
 0.733
LBA0436
N-acetylglucosamine catabolic protein.
     
 0.701
LBA1606
Integral membrane protein putative.
 
  
 0.699
mprF
Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
     
 0.671
LBA1115
COG0531 Amino acid transporters.
 
    0.590
dltD
Extramembranal transfer protein; DltD; COG3966 protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid.
 
  
 0.558
LBA1132
Lactococcin A ABC transporter ATP binding protein.
 
     0.535
vanZ
Putative membrane protein; VanZ.
      
 0.530
LBA0037
COG4905 Predicted membrane protein.
  
     0.528
lytR
LytR; COG1316 transcriptional regulator.
     
 0.525
Your Current Organism:
Lactobacillus acidophilus
NCBI taxonomy Id: 272621
Other names: L. acidophilus NCFM, Lactobacillus acidophilus NCFM, Lactobacillus acidophilus str. NCFM, Lactobacillus acidophilus strain NCFM
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.