STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pleDSensor histidine kinase. (709 aa)    
Predicted Functional Partners:
lpg1114
Sensory box protein (GGDEF domain/EAL domain).
 
 0.991
lpg0073
Diguanylate cyclase/phosphodiesterase domain 2.
 
 0.988
lpg0829
Two component histidine kinase, GGDEF domain protein/EAL domain protein.
 
 
 0.982
lpg2180
Sensory box histidine kinase/response regulator.
 0.975
lpg1518
Sensory box protein/GGDEF domain/EAL domain.
 
 
0.969
lpg1912
Sensory box histidine kinase/response regulator.
 
 0.969
rsbV
Hypothetical protein.
  
 
 0.962
leuS
Leucyl tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
   
   0.952
lpg1469
Rtn protein.
 
 0.938
lpg0277
Sensory box protein, GGDEF family protein, LssE.
 
0.936
Your Current Organism:
Legionella pneumophila Philadelphia
NCBI taxonomy Id: 272624
Other names: L. pneumophila subsp. pneumophila str. Philadelphia 1, Legionella pneumophila subsp. pneumophila str. Philadelphia 1, Legionella pneumophila subsp. pneumophila str. Philadelphia-1, Legionella pneumophila subsp. pneumophila strain Philadelphia 1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.