STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fixLSensor histidine kinase. (471 aa)    
Predicted Functional Partners:
lpg0277
Sensory box protein, GGDEF family protein, LssE.
 
 0.998
lpg1912
Sensory box histidine kinase/response regulator.
 
 0.996
lpg2146
Response regulator TutC.
 
 0.994
lpg2180
Sensory box histidine kinase/response regulator.
 
0.994
lpg2181
Sensory box sensor histidine kinase/response regulator, putative.
 
 0.991
lpg2732
(two component) response regulator.
 
 0.975
lpg2145
Two component response regulator, CheY homologous receiver domain).
  
 0.966
cpxR
Transcriptional regulatory protein CpxR.
 
 
 0.961
lpg1292
DNA-binding response regulator.
 
 
 0.959
lpg0715
Two component response regulator.
   
 0.951
Your Current Organism:
Legionella pneumophila Philadelphia
NCBI taxonomy Id: 272624
Other names: L. pneumophila subsp. pneumophila str. Philadelphia 1, Legionella pneumophila subsp. pneumophila str. Philadelphia 1, Legionella pneumophila subsp. pneumophila str. Philadelphia-1, Legionella pneumophila subsp. pneumophila strain Philadelphia 1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.