node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
glyA3 | lpg0604 | lpg0725 | lpg0604 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Aminotransferase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. | 0.695 |
glyA3 | lpg0606 | lpg0725 | lpg0606 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Metal-sulfur cluster biosynthetic enzyme. | 0.632 |
lpg0469 | lpg0604 | lpg0469 | lpg0604 | Endonuclease/exonuclease/phosphatase family protein. | Aminotransferase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. | 0.964 |
lpg0600 | lpg0602 | lpg0600 | lpg0602 | Rrf2 family protein. | ATP transporter, ABC binding component, ATP-binding protein. | 0.820 |
lpg0600 | lpg0603 | lpg0600 | lpg0603 | Rrf2 family protein. | ABC transporter, permease component. | 0.856 |
lpg0600 | lpg0604 | lpg0600 | lpg0604 | Rrf2 family protein. | Aminotransferase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. | 0.825 |
lpg0600 | lpg0605 | lpg0600 | lpg0605 | Rrf2 family protein. | Nitrogen fixation protein (Fe-S cluster formation) NifU. | 0.992 |
lpg0600 | lpg0606 | lpg0600 | lpg0606 | Rrf2 family protein. | Metal-sulfur cluster biosynthetic enzyme. | 0.696 |
lpg0600 | lpg0607 | lpg0600 | lpg0607 | Rrf2 family protein. | Lysyl tRNA synthetase. | 0.696 |
lpg0600 | lpg1745 | lpg0600 | lpg1745 | Rrf2 family protein. | NifU family iron binding protein, [Fe-S] cluster formation/repair protein IscU, HesB. | 0.449 |
lpg0600 | ycf24 | lpg0600 | lpg0601 | Rrf2 family protein. | ABC transporter, permease. | 0.833 |
lpg0602 | lpg0600 | lpg0602 | lpg0600 | ATP transporter, ABC binding component, ATP-binding protein. | Rrf2 family protein. | 0.820 |
lpg0602 | lpg0603 | lpg0602 | lpg0603 | ATP transporter, ABC binding component, ATP-binding protein. | ABC transporter, permease component. | 0.999 |
lpg0602 | lpg0604 | lpg0602 | lpg0604 | ATP transporter, ABC binding component, ATP-binding protein. | Aminotransferase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. | 0.998 |
lpg0602 | lpg0605 | lpg0602 | lpg0605 | ATP transporter, ABC binding component, ATP-binding protein. | Nitrogen fixation protein (Fe-S cluster formation) NifU. | 0.974 |
lpg0602 | lpg0606 | lpg0602 | lpg0606 | ATP transporter, ABC binding component, ATP-binding protein. | Metal-sulfur cluster biosynthetic enzyme. | 0.923 |
lpg0602 | lpg0607 | lpg0602 | lpg0607 | ATP transporter, ABC binding component, ATP-binding protein. | Lysyl tRNA synthetase. | 0.696 |
lpg0602 | lpg1745 | lpg0602 | lpg1745 | ATP transporter, ABC binding component, ATP-binding protein. | NifU family iron binding protein, [Fe-S] cluster formation/repair protein IscU, HesB. | 0.856 |
lpg0602 | ycf24 | lpg0602 | lpg0601 | ATP transporter, ABC binding component, ATP-binding protein. | ABC transporter, permease. | 0.999 |
lpg0603 | lpg0600 | lpg0603 | lpg0600 | ABC transporter, permease component. | Rrf2 family protein. | 0.856 |