STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lpg0604Aminotransferase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. (414 aa)    
Predicted Functional Partners:
lpg0605
Nitrogen fixation protein (Fe-S cluster formation) NifU.
 
 0.999
lpg0602
ATP transporter, ABC binding component, ATP-binding protein.
 
  
 0.998
ycf24
ABC transporter, permease.
 
 
 0.993
lpg0603
ABC transporter, permease component.
 
 
 0.993
lpg1745
NifU family iron binding protein, [Fe-S] cluster formation/repair protein IscU, HesB.
  
 0.991
lpg0469
Endonuclease/exonuclease/phosphatase family protein.
    
   0.964
lpg0606
Metal-sulfur cluster biosynthetic enzyme.
 
  
 0.869
lpg0600
Rrf2 family protein.
 
     0.825
lpg0607
Lysyl tRNA synthetase.
       0.696
glyA3
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.695
Your Current Organism:
Legionella pneumophila Philadelphia
NCBI taxonomy Id: 272624
Other names: L. pneumophila subsp. pneumophila str. Philadelphia 1, Legionella pneumophila subsp. pneumophila str. Philadelphia 1, Legionella pneumophila subsp. pneumophila str. Philadelphia-1, Legionella pneumophila subsp. pneumophila strain Philadelphia 1
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