Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
lpg0806Na+/H+ antiporter. (479 aa)    
Predicted Functional Partners:
nadC
Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family.
       0.862
murG
Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.
       0.862
dapE
Succinyl-diaminopimelate desuccinylase.
       0.862
lpg0810
Hypothetical protein; Transport and binding, Transcription factors / DNA binding proteins.
       0.752
lpg0805
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
       0.700
lpg1507
Sodium/hydrogen antiporter.
 
   
 0.643
mreB
Rod shape determining protein MreB.
  
    0.592
mreC
Rod shape determining protein MreC; Involved in formation and maintenance of cell shape.
       0.565
mreD
Rod shape determining protein MreD.
       0.543
nadA
Quinolinate synthetase A (NadA); Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
       0.506
Your Current Organism:
Legionella pneumophila Philadelphia
NCBI taxonomy Id: 272624
Other names: L. pneumophila subsp. pneumophila str. Philadelphia 1, Legionella pneumophila subsp. pneumophila str. Philadelphia 1, Legionella pneumophila subsp. pneumophila str. Philadelphia-1, Legionella pneumophila subsp. pneumophila strain Philadelphia 1
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