STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lpg1291Two component sensor kinase. (471 aa)    
Predicted Functional Partners:
lpg2180
Sensory box histidine kinase/response regulator.
 
0.994
lpg2146
Response regulator TutC.
 
0.991
lpg1292
DNA-binding response regulator.
 
 0.990
lpg1912
Sensory box histidine kinase/response regulator.
 
0.981
lpg2181
Sensory box sensor histidine kinase/response regulator, putative.
 
 
 0.945
lpg2581
2-oxoisovalerate dehydrogenase, E1 component, alpha and beta fusion.
    
 0.910
lpg0715
Two component response regulator.
 
 0.882
cpxR
Transcriptional regulatory protein CpxR.
 
 0.877
lpg0184
ABC sugar transporter, periplasmic sugar binding protein.
    
 0.846
fixL
Sensor histidine kinase.
 
 
 0.843
Your Current Organism:
Legionella pneumophila Philadelphia
NCBI taxonomy Id: 272624
Other names: L. pneumophila subsp. pneumophila str. Philadelphia 1, Legionella pneumophila subsp. pneumophila str. Philadelphia 1, Legionella pneumophila subsp. pneumophila str. Philadelphia-1, Legionella pneumophila subsp. pneumophila strain Philadelphia 1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.