Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
lpg1612Transcriptional regulator SkgA, mercury resistance. (250 aa)    
Predicted Functional Partners:
yqkA
Glutamate rich protein GrpB.
 
     0.790
lpg1613
Acetyltransferase, GNAT family.
 
     0.673
lpg1611
Transcriptional regulator, MerR family, mercury resistance.
 
 
  
0.605
abcT3-2
Multidrug resistance ABC transporter ATP binding protein.
  
    0.592
uup
ABC transporter ATP-binding protein Uup, erythromycin resistance.
       0.584
rpoB
DNA-directed RNA polymerase beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.555
rre41
Sensory box (GGDEF/EAL domain) regulatory protein.
    
  0.500
lpg0891
Sensory box protein/GGDEF/EAL domains.
    
  0.500
lpg1357
Inner membrane protein PLUS sensory box protein LssE.
    
  0.500
queF
GTP cyclohydrolase I PLUS perhaps regulatory protein; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
     
 0.480
Your Current Organism:
Legionella pneumophila Philadelphia
NCBI taxonomy Id: 272624
Other names: L. pneumophila subsp. pneumophila str. Philadelphia 1, Legionella pneumophila subsp. pneumophila str. Philadelphia 1, Legionella pneumophila subsp. pneumophila str. Philadelphia-1, Legionella pneumophila subsp. pneumophila strain Philadelphia 1
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