Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
lpg1645Hypothetical protein; Belongs to the UPF0312 family. (191 aa)    
Predicted Functional Partners:
lpg1647
Hypothetical protein; Belongs to the UPF0312 family.
 
     0.967
lpg1646
Cytochrome b561 transmembrane protein.
  
 0.963
lpg1648
Signal peptide protein.
       0.835
lpg1580
Cytochrome b-561 transmembrane protein.
  
 0.772
lpg2253
Hypothetical protein.
       0.506
lpg2254
Hypothetical protein; Belongs to the UPF0276 family.
       0.506
iolE
Myo-inositol catabolism protein IolE.
       0.468
iolD
Myo-inositol catabolism protein IolD; Belongs to the TPP enzyme family.
       0.468
lpg1644
Hypothetical protein.
       0.432
lpg1651
IolC/IolB transferase kinase protein.
       0.404
Your Current Organism:
Legionella pneumophila Philadelphia
NCBI taxonomy Id: 272624
Other names: L. pneumophila subsp. pneumophila str. Philadelphia 1, Legionella pneumophila subsp. pneumophila str. Philadelphia 1, Legionella pneumophila subsp. pneumophila str. Philadelphia-1, Legionella pneumophila subsp. pneumophila strain Philadelphia 1
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