Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
lpg1925Hypothetical protein. (881 aa)    
Predicted Functional Partners:
lpg1924
Hypothetical protein.
     
 0.775
lpg1926
Hypothetical protein.
       0.769
indA
Indigoidine synthase A-like protein, uncharacterized enzyme involved in pigment biosynthesis; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family.
       0.637
lpg1927
Hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
       0.623
lpg0782
O-antigen acetylase.
      
 0.618
lpg1316
Hypothetical protein.
      
 0.618
legK1
Similar to ovarian-specific serine/threonine-protein kinase; conserved gene.
      
 0.618
lpg1934
Hypothetical protein; Signal transduction / other regulatory functions, Transcription factors / DNA binding proteins.
      
 0.618
lpg2368
Hypothetical protein; Transcription factors / DNA binding proteins.
      
 0.618
lpg2369
HipA (persistence to inhibition of murein or DNA biosynthesis).
      
 0.618
Your Current Organism:
Legionella pneumophila Philadelphia
NCBI taxonomy Id: 272624
Other names: L. pneumophila subsp. pneumophila str. Philadelphia 1, Legionella pneumophila subsp. pneumophila str. Philadelphia 1, Legionella pneumophila subsp. pneumophila str. Philadelphia-1, Legionella pneumophila subsp. pneumophila strain Philadelphia 1
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.