Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
lpg1982Hypothetical protein. (347 aa)    
Predicted Functional Partners:
lpg1981
Hypothetical protein.
       0.701
lpg1983
Hypothetical; 3-hydroxy-3-methylglutaryl coenzyme A reductase-like.
  
    0.629
legA14
Ankyrin repeat-containing protein.
  
 
   0.607
lpg2240
Dipeptidyl aminopeptidase/acylaminoacyl peptidase.
  
 
  0.565
lpg0680
Dipeptidyl aminopeptidase/acylaminoacyl peptidase.
  
     0.516
lpg2403
Hypothetical protein.
   
 0.501
lpg1044
Oxidoreductase, FAD-binding.
     
 0.481
lpg2536
Ferredoxin reductase.
     
 0.480
tpm
Thiopurine S-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
  
 
  0.477
lpg2537
5-carboxyvanillate decarboxylase.
 
    0.471
Your Current Organism:
Legionella pneumophila Philadelphia
NCBI taxonomy Id: 272624
Other names: L. pneumophila subsp. pneumophila str. Philadelphia 1, Legionella pneumophila subsp. pneumophila str. Philadelphia 1, Legionella pneumophila subsp. pneumophila str. Philadelphia-1, Legionella pneumophila subsp. pneumophila strain Philadelphia 1
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