Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
lpg1997Hypothetical protein. (104 aa)    
Predicted Functional Partners:
lpg1996
Hypothetical protein.
  
    0.864
lpg1995
Hypothetical protein.
       0.862
xcpW
General secretion pathway protein LspJ.
  
 0.809
lpg1994
(outer) membrane bound lytic murein transglycosylase family protein; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.
       0.743
lpg1319
Type II secretory pathway protein E; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.
  
 0.728
pilB
(type IV) pilus assembly protein PilB.
  
 0.728
xcpX
General secretion pathway protein LspK.
   
 
 0.724
lpg1999
Pterin 4 alpha carbinolamine dehydratase.
       0.713
gspF
Type II protein secretion LspF.
  
  
 0.640
pilC
(type IV) pilus assembly protein PilC.
  
  
 0.640
Your Current Organism:
Legionella pneumophila Philadelphia
NCBI taxonomy Id: 272624
Other names: L. pneumophila subsp. pneumophila str. Philadelphia 1, Legionella pneumophila subsp. pneumophila str. Philadelphia 1, Legionella pneumophila subsp. pneumophila str. Philadelphia-1, Legionella pneumophila subsp. pneumophila strain Philadelphia 1
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