STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lpg2264Hypothetical protein; Transcription factors / DNA binding proteins. (104 aa)    
Predicted Functional Partners:
cbpA
Curved DNA binding protein DnaJ.
 
 
 0.997
dnaJ
Heat shock protein DnaJ, chaperone protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interact [...]
  
 
 0.910
lpg2261
Phosphate acetyl/butyryltransferase family protein) includes: (de)hydratase mit MaoC domain).
    
  0.770
ackA2
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
       0.685
phbC-3
PHA synthase.
       0.638
lpg2180
Sensory box histidine kinase/response regulator.
    
 0.626
lpg2018
Hypothetical protein.
  
     0.617
rre41
Sensory box (GGDEF/EAL domain) regulatory protein.
    
 0.602
lpg0891
Sensory box protein/GGDEF/EAL domains.
    
 0.602
lpg1357
Inner membrane protein PLUS sensory box protein LssE.
    
 0.602
Your Current Organism:
Legionella pneumophila Philadelphia
NCBI taxonomy Id: 272624
Other names: L. pneumophila subsp. pneumophila str. Philadelphia 1, Legionella pneumophila subsp. pneumophila str. Philadelphia 1, Legionella pneumophila subsp. pneumophila str. Philadelphia-1, Legionella pneumophila subsp. pneumophila strain Philadelphia 1
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