STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sdaCSerine transporter. (453 aa)    
Predicted Functional Partners:
dnaK
Chaperone protein DnaK, heat shock protein Hsp70; Acts as a chaperone; Belongs to the heat shock protein 70 family.
    
  0.824
legS2
Sphingosine-1-phosphate lyase I; Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine (By similarity). Possibly implicated in influencing the macrophage autophagy pathway.
     
 0.747
lpg1042
Hypothetical protein.
  
  
  0.655
sda-2
L-serine dehydratase (iron, sulfur-dependent); Belongs to the iron-sulfur dependent L-serine dehydratase family.
 
  
 0.594
htpG
Chaperone Hsp90 HtpG; Molecular chaperone. Has ATPase activity.
    
  0.512
lpg2320
Hypothetical protein.
       0.508
pagP
Rcp; Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors.
  
     0.462
tehB
Tellurite resistance protein.
  
 
   0.453
lpg0998
Hypothetical protein.
  
     0.450
lpg1000
Putative exported protein.
  
     0.435
Your Current Organism:
Legionella pneumophila Philadelphia
NCBI taxonomy Id: 272624
Other names: L. pneumophila subsp. pneumophila str. Philadelphia 1, Legionella pneumophila subsp. pneumophila str. Philadelphia 1, Legionella pneumophila subsp. pneumophila str. Philadelphia-1, Legionella pneumophila subsp. pneumophila strain Philadelphia 1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.