Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
lpg2425Hypothetical protein. (268 aa)    
Predicted Functional Partners:
mdcA
Malonate decarboxylase alpha subunit.
       0.422
mdcB
Acetyl coenzyme A carboxylase, carboxyltransferase subunit beta; Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism.
       0.422
mdcC
Malonate decarboxylase gamma subunit.
       0.422
mdcG
Nucleotidyltransferases.
       0.422
mdcB-2
2(5'-triphosphoribosyl)-3'-dephosphocoenzyme A synthase CitG, modifier of citrate lyase.
       0.422
lpg2431
Putative malonyl-CoA acyl-carrier-protein transacylase.
       0.422
Your Current Organism:
Legionella pneumophila Philadelphia
NCBI taxonomy Id: 272624
Other names: L. pneumophila subsp. pneumophila str. Philadelphia 1, Legionella pneumophila subsp. pneumophila str. Philadelphia 1, Legionella pneumophila subsp. pneumophila str. Philadelphia-1, Legionella pneumophila subsp. pneumophila strain Philadelphia 1
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