node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
dinG | dnaN | gene:17566371 | gene:17564313 | 3'-5' exonuclease DinG; 3'-5' exonuclease. | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | 0.975 |
dinG | lin1993 | gene:17566371 | gene:17566351 | 3'-5' exonuclease DinG; 3'-5' exonuclease. | Lin1993 protein; Similar to similar to RNase HI. | 0.548 |
dinG | polA | gene:17566371 | gene:17565931 | 3'-5' exonuclease DinG; 3'-5' exonuclease. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.903 |
dinG | rnhB | gene:17566371 | gene:17565643 | 3'-5' exonuclease DinG; 3'-5' exonuclease. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.703 |
dnaN | dinG | gene:17564313 | gene:17566371 | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | 3'-5' exonuclease DinG; 3'-5' exonuclease. | 0.975 |
dnaN | lin1988 | gene:17564313 | gene:17566346 | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.743 |
dnaN | polA | gene:17564313 | gene:17565931 | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.990 |
dnaN | rnhB | gene:17564313 | gene:17565643 | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.924 |
lin1308 | lin1309 | gene:17565639 | gene:17565640 | Similar to type-I signal peptidase; Belongs to the peptidase S26 family. | Similar to signal peptidase I; Belongs to the peptidase S26 family. | 0.973 |
lin1308 | lin1310 | gene:17565639 | gene:17565641 | Similar to type-I signal peptidase; Belongs to the peptidase S26 family. | Similar to signal peptidase I; Belongs to the peptidase S26 family. | 0.965 |
lin1308 | lin1311 | gene:17565639 | gene:17565642 | Similar to type-I signal peptidase; Belongs to the peptidase S26 family. | Ribosome biogenesis GTPase A; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | 0.534 |
lin1308 | lin1313 | gene:17565639 | gene:17565644 | Similar to type-I signal peptidase; Belongs to the peptidase S26 family. | Lin1313 protein; Similar to polypeptide deformylase, similar to B. subtilis Smf protein. | 0.457 |
lin1308 | rnhB | gene:17565639 | gene:17565643 | Similar to type-I signal peptidase; Belongs to the peptidase S26 family. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.708 |
lin1309 | lin1308 | gene:17565640 | gene:17565639 | Similar to signal peptidase I; Belongs to the peptidase S26 family. | Similar to type-I signal peptidase; Belongs to the peptidase S26 family. | 0.973 |
lin1309 | lin1310 | gene:17565640 | gene:17565641 | Similar to signal peptidase I; Belongs to the peptidase S26 family. | Similar to signal peptidase I; Belongs to the peptidase S26 family. | 0.983 |
lin1309 | lin1311 | gene:17565640 | gene:17565642 | Similar to signal peptidase I; Belongs to the peptidase S26 family. | Ribosome biogenesis GTPase A; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | 0.593 |
lin1309 | lin1313 | gene:17565640 | gene:17565644 | Similar to signal peptidase I; Belongs to the peptidase S26 family. | Lin1313 protein; Similar to polypeptide deformylase, similar to B. subtilis Smf protein. | 0.463 |
lin1309 | rnhB | gene:17565640 | gene:17565643 | Similar to signal peptidase I; Belongs to the peptidase S26 family. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.746 |
lin1310 | lin1308 | gene:17565641 | gene:17565639 | Similar to signal peptidase I; Belongs to the peptidase S26 family. | Similar to type-I signal peptidase; Belongs to the peptidase S26 family. | 0.965 |
lin1310 | lin1309 | gene:17565641 | gene:17565640 | Similar to signal peptidase I; Belongs to the peptidase S26 family. | Similar to signal peptidase I; Belongs to the peptidase S26 family. | 0.983 |