node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
lin0439 | polA | gene:17564766 | gene:17565931 | Lin0439 protein. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.434 |
lin0439 | recA | gene:17564766 | gene:17565766 | Lin0439 protein. | Recombination protein recA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.888 |
lin0439 | recN | gene:17564766 | gene:17565736 | Lin0439 protein. | DNA repair and genetic recombination; May be involved in recombinational repair of damaged DNA. | 0.555 |
lin0439 | topA | gene:17564766 | gene:17565645 | Lin0439 protein. | DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.412 |
lin1340 | polA | gene:17565671 | gene:17565931 | LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.434 |
lin1340 | recA | gene:17565671 | gene:17565766 | LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | Recombination protein recA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.975 |
lin1340 | recN | gene:17565671 | gene:17565736 | LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | DNA repair and genetic recombination; May be involved in recombinational repair of damaged DNA. | 0.579 |
lin1340 | topA | gene:17565671 | gene:17565645 | LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.412 |
lin1801 | pcrA | gene:17566156 | gene:17566226 | Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family. | ATP-dependent DNA helicase. | 0.429 |
lin1801 | polA | gene:17566156 | gene:17565931 | Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.525 |
lin1801 | recA | gene:17566156 | gene:17565766 | Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family. | Recombination protein recA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.925 |
lin1801 | recN | gene:17566156 | gene:17565736 | Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family. | DNA repair and genetic recombination; May be involved in recombinational repair of damaged DNA. | 0.612 |
lin1801 | topA | gene:17566156 | gene:17565645 | Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family. | DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.543 |
lin2900 | pcrA | gene:17567286 | gene:17566226 | Lin2900 protein; Similar to ATP-dependent DNA helicases. | ATP-dependent DNA helicase. | 0.855 |
lin2900 | polA | gene:17567286 | gene:17565931 | Lin2900 protein; Similar to ATP-dependent DNA helicases. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.868 |
lin2900 | recA | gene:17567286 | gene:17565766 | Lin2900 protein; Similar to ATP-dependent DNA helicases. | Recombination protein recA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.854 |
lin2900 | topA | gene:17567286 | gene:17565645 | Lin2900 protein; Similar to ATP-dependent DNA helicases. | DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.976 |
pcrA | lin1801 | gene:17566226 | gene:17566156 | ATP-dependent DNA helicase. | Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family. | 0.429 |
pcrA | lin2900 | gene:17566226 | gene:17567286 | ATP-dependent DNA helicase. | Lin2900 protein; Similar to ATP-dependent DNA helicases. | 0.855 |
pcrA | polA | gene:17566226 | gene:17565931 | ATP-dependent DNA helicase. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.778 |