STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemCPorphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (309 aa)    
Predicted Functional Partners:
lin1164
Lin1164 protein; Similar uroporphyrinogen-III methyltransferase/uroporphyrinogen-III synthase.
 0.999
hemB
Highly similar to delta-aminolevulinic acid dehydratases (porphobilinogen synthase); Belongs to the ALAD family.
 
 0.999
lin1590
Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
 
 0.998
hemA
Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
  
 0.997
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
 0.996
hemL
Highly similar to glutamate-1-semialdehyde 2,1-aminotransferases.
 
  
 0.994
gsaB
Glutamate-1-semialdehyde aminotransferase.
 
  
 0.954
lin1105
Lin1105 protein; Similar to uroporphyrin-III C-methyltransferase.
 
  
 0.815
cbiF
CbiF protein; Similar to precorrin-3 methylase.
   
 0.788
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
 
  
 0.768
Your Current Organism:
Listeria innocua
NCBI taxonomy Id: 272626
Other names: L. innocua Clip11262, Listeria innocua Clip11262, Listeria innocua str. Clip11262, Listeria innocua strain Clip11262
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.