node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
lin1844 | pyrAB | gene:17566200 | gene:17566307 | Lin1844 protein; Similar to glutamate synthase (small subunit). | Carbamoyl-phosphate synthase large chain; Highly similar to carbamoyl-phosphate synthetase (catalytic subunit). | 0.922 |
lin1844 | pyrAa | gene:17566200 | gene:17566308 | Lin1844 protein; Similar to glutamate synthase (small subunit). | Carbamoyl-phosphate synthase small chain; Highly similar to carbamoyl-phosphate synthetase (glutaminase subunit); Belongs to the CarA family. | 0.909 |
lin1844 | pyrD | gene:17566200 | gene:17566305 | Lin1844 protein; Similar to glutamate synthase (small subunit). | Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily. | 0.913 |
lin1844 | pyrDII | gene:17566200 | gene:17566306 | Lin1844 protein; Similar to glutamate synthase (small subunit). | Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). | 0.976 |
pyrAB | lin1844 | gene:17566307 | gene:17566200 | Carbamoyl-phosphate synthase large chain; Highly similar to carbamoyl-phosphate synthetase (catalytic subunit). | Lin1844 protein; Similar to glutamate synthase (small subunit). | 0.922 |
pyrAB | pyrAa | gene:17566307 | gene:17566308 | Carbamoyl-phosphate synthase large chain; Highly similar to carbamoyl-phosphate synthetase (catalytic subunit). | Carbamoyl-phosphate synthase small chain; Highly similar to carbamoyl-phosphate synthetase (glutaminase subunit); Belongs to the CarA family. | 0.999 |
pyrAB | pyrB | gene:17566307 | gene:17566310 | Carbamoyl-phosphate synthase large chain; Highly similar to carbamoyl-phosphate synthetase (catalytic subunit). | Highly similar to aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
pyrAB | pyrC | gene:17566307 | gene:17566309 | Carbamoyl-phosphate synthase large chain; Highly similar to carbamoyl-phosphate synthetase (catalytic subunit). | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.999 |
pyrAB | pyrD | gene:17566307 | gene:17566305 | Carbamoyl-phosphate synthase large chain; Highly similar to carbamoyl-phosphate synthetase (catalytic subunit). | Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily. | 0.997 |
pyrAB | pyrDII | gene:17566307 | gene:17566306 | Carbamoyl-phosphate synthase large chain; Highly similar to carbamoyl-phosphate synthetase (catalytic subunit). | Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). | 0.994 |
pyrAB | pyrE | gene:17566307 | gene:17566303 | Carbamoyl-phosphate synthase large chain; Highly similar to carbamoyl-phosphate synthetase (catalytic subunit). | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.995 |
pyrAB | pyrF | gene:17566307 | gene:17566304 | Carbamoyl-phosphate synthase large chain; Highly similar to carbamoyl-phosphate synthetase (catalytic subunit). | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.996 |
pyrAB | pyrP | gene:17566307 | gene:17566311 | Carbamoyl-phosphate synthase large chain; Highly similar to carbamoyl-phosphate synthetase (catalytic subunit). | PyrP protein; Highly similar to uracil permease. | 0.940 |
pyrAB | pyrR | gene:17566307 | gene:17566312 | Carbamoyl-phosphate synthase large chain; Highly similar to carbamoyl-phosphate synthetase (catalytic subunit). | Pyrimidine operon regulatory protein; Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes. Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. | 0.935 |
pyrAa | lin1844 | gene:17566308 | gene:17566200 | Carbamoyl-phosphate synthase small chain; Highly similar to carbamoyl-phosphate synthetase (glutaminase subunit); Belongs to the CarA family. | Lin1844 protein; Similar to glutamate synthase (small subunit). | 0.909 |
pyrAa | pyrAB | gene:17566308 | gene:17566307 | Carbamoyl-phosphate synthase small chain; Highly similar to carbamoyl-phosphate synthetase (glutaminase subunit); Belongs to the CarA family. | Carbamoyl-phosphate synthase large chain; Highly similar to carbamoyl-phosphate synthetase (catalytic subunit). | 0.999 |
pyrAa | pyrB | gene:17566308 | gene:17566310 | Carbamoyl-phosphate synthase small chain; Highly similar to carbamoyl-phosphate synthetase (glutaminase subunit); Belongs to the CarA family. | Highly similar to aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
pyrAa | pyrC | gene:17566308 | gene:17566309 | Carbamoyl-phosphate synthase small chain; Highly similar to carbamoyl-phosphate synthetase (glutaminase subunit); Belongs to the CarA family. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.999 |
pyrAa | pyrD | gene:17566308 | gene:17566305 | Carbamoyl-phosphate synthase small chain; Highly similar to carbamoyl-phosphate synthetase (glutaminase subunit); Belongs to the CarA family. | Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily. | 0.985 |
pyrAa | pyrDII | gene:17566308 | gene:17566306 | Carbamoyl-phosphate synthase small chain; Highly similar to carbamoyl-phosphate synthetase (glutaminase subunit); Belongs to the CarA family. | Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). | 0.978 |