| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CCC_02452 | CCC_03195 | CCC_02452 | CCC_03195 | Porphobilinogen synthase; Belongs to the ALAD family. | Uroporphyrinogen-III methyltransferase; Belongs to the precorrin methyltransferase family. | 0.929 |
| CCC_02452 | CCC_03813 | CCC_02452 | CCC_03813 | Porphobilinogen synthase; Belongs to the ALAD family. | Uroporphyrinogen-III methyltransferase; Belongs to the precorrin methyltransferase family. | 0.924 |
| CCC_02452 | hemA | CCC_02452 | CCC_03067 | Porphobilinogen synthase; Belongs to the ALAD family. | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.892 |
| CCC_02452 | hemC | CCC_02452 | CCC_01041 | Porphobilinogen synthase; Belongs to the ALAD family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.997 |
| CCC_03195 | CCC_02452 | CCC_03195 | CCC_02452 | Uroporphyrinogen-III methyltransferase; Belongs to the precorrin methyltransferase family. | Porphobilinogen synthase; Belongs to the ALAD family. | 0.929 |
| CCC_03195 | CCC_03813 | CCC_03195 | CCC_03813 | Uroporphyrinogen-III methyltransferase; Belongs to the precorrin methyltransferase family. | Uroporphyrinogen-III methyltransferase; Belongs to the precorrin methyltransferase family. | 0.927 |
| CCC_03195 | hemA | CCC_03195 | CCC_03067 | Uroporphyrinogen-III methyltransferase; Belongs to the precorrin methyltransferase family. | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.847 |
| CCC_03195 | hemC | CCC_03195 | CCC_01041 | Uroporphyrinogen-III methyltransferase; Belongs to the precorrin methyltransferase family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.995 |
| CCC_03813 | CCC_02452 | CCC_03813 | CCC_02452 | Uroporphyrinogen-III methyltransferase; Belongs to the precorrin methyltransferase family. | Porphobilinogen synthase; Belongs to the ALAD family. | 0.924 |
| CCC_03813 | CCC_03195 | CCC_03813 | CCC_03195 | Uroporphyrinogen-III methyltransferase; Belongs to the precorrin methyltransferase family. | Uroporphyrinogen-III methyltransferase; Belongs to the precorrin methyltransferase family. | 0.927 |
| CCC_03813 | hemA | CCC_03813 | CCC_03067 | Uroporphyrinogen-III methyltransferase; Belongs to the precorrin methyltransferase family. | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.830 |
| CCC_03813 | hemC | CCC_03813 | CCC_01041 | Uroporphyrinogen-III methyltransferase; Belongs to the precorrin methyltransferase family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.995 |
| gltX | gltX-2 | CCC_02598 | CCC_03675 | Glutamyl-tRNA(Gln) synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | Glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | 0.935 |
| gltX | hemA | CCC_02598 | CCC_03067 | Glutamyl-tRNA(Gln) synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.932 |
| gltX-2 | gltX | CCC_03675 | CCC_02598 | Glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | Glutamyl-tRNA(Gln) synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | 0.935 |
| gltX-2 | hemA | CCC_03675 | CCC_03067 | Glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.932 |
| gltX-2 | prfA | CCC_03675 | CCC_03068 | Glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | 0.451 |
| hemA | CCC_02452 | CCC_03067 | CCC_02452 | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Porphobilinogen synthase; Belongs to the ALAD family. | 0.892 |
| hemA | CCC_03195 | CCC_03067 | CCC_03195 | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Uroporphyrinogen-III methyltransferase; Belongs to the precorrin methyltransferase family. | 0.847 |
| hemA | CCC_03813 | CCC_03067 | CCC_03813 | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Uroporphyrinogen-III methyltransferase; Belongs to the precorrin methyltransferase family. | 0.830 |